Closed-Loop and Activity-Guided Optogenetic Control

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Closed-Loop and Activity-Guided Optogenetic Control

Advances in optical manipulation and observation of neural activity have set the stage for widespread implementation of closed-loop and activity-guided optical control of neural circuit dynamics. Closing the loop optogenetically (i.e., basing optogenetic stimulation on simultaneously observed dynamics in a principled way) is a powerful strategy for causal investigation of neural circuitry. In p...

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Design strategies for dynamic closed-loop optogenetic neurocontrol in vivo.

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ژورنال

عنوان ژورنال: Neuron

سال: 2015

ISSN: 0896-6273

DOI: 10.1016/j.neuron.2015.03.034